Building on over 15 years of discovery, our dedicated team of researchers continue to meet the challenge of changing research into patient-centered solutions.
Exosome Powered Therapies
Not all exosomes are created equally, and different subtypes often carry drastically different cargo in their native state. We have discovered that some exosomes carry potent proteins which promote new blood vessel formation and cell migration, while others are not nearly as active but are ideal for use in gene therapy and drug delivery. Using our proprietary manufacturing process, we have the ability to harness the power of each subtype of exosome.
Using our potent regenerative exosomes in combination with existing and novel bioscaffolds such as collagen, our researchs are focused on unique ways to restore damaged tissue. By harnessing specific exosome subtypes (such as PEP), our team has may several key discovers in providing damaged tissue with the key angiogenic, vascular, and growth stimulating proteins required to restore both structure and function.
Similar to drug delivery, altering the cargo of naturally occurring exosomes to contain DNA and RNA holds the potential to cure diseases that we once thought were incurable. Our team is hard at work developing techniques to use exosomes as carriers of genetic material to treat a variety of disease states, from acute myocardial infarction to cystic fibrosis.
Our regenerative exosomes are powerful on their own, but the potential to alter the cargo of exosomes to carry a specific drug to a diseased portion of the body would stand as a breakthrough in cancer therapy. Our research team has generated promising data for the treatment of diffuse intrinsic pontine glioma, a devastating pediatric cancer that currently has very limited treatments, using exosomes in combination with a novel small molecule drug.